The epidemiology of depression in diabetes

Authors

  • K Winkley

DOI:

https://doi.org/10.1002/edn.117

Keywords:

Diabetes, depression

Abstract

Abstract

Depression is characterised by a period of low mood and loss of interest in everyday activities, and its prevalence in people with diabetes is thought to be twice as high as for those without the condition. Depression in diabetes is associated with a number of adverse outcomes such as increased morbidity, mortality and poor quality of life. As diabetes is increasingly common amongst the economically active, this has serious implications for health services and in the UK, the National Health Service (NHS) has recognised that depression in people with diabetes is a significant problem and recommends screening for depression in this group. Risk factors for depression in diabetes are almost identical to those in people without diabetes, but less is known about its course when people have diabetes, although the available evidence suggests it is more chronic. Research into the mechanisms by which depression is bad for people with diabetes suggests that biological, psychological and social factors play a part but the inter-relationships between these factors are likely to be complex and are not yet fully understood. Depression in people with diabetes can be treated successfully with pharmacological and psychological treatments at least in the short-term, but we do not yet know which treatments are successful in the long-term. Further research into the pathological mechanisms of depression and its treatment are needed if we are to continue to improve the health and lives of people with diabetes.

Downloads

Download data is not yet available.

References

Beeney L, Bakry A, Dunn S, Patient psy-chological and information needs when the diagnosis is diabetes. Patient Education & Counseling 1996; 29: 109–116.

Jacobson AM. The psychological care of patients with insulin-dependent dia-betes mellitus. N Engi J Med 1996; 334: 1249–1253.

Snoek FJ, Skinner TC. Psychological counselling in problematic diabetes: does it help? Diabetic Med 2002; 19: 265–273.

WHO. The ICD- 10 classification of mental and behavioural disorders. Clinical descriptions and diagnosticguidelines. Geneva: World Health Organization, 1992.

APA. Diagnostic and statistical manual of mental disorders, text revision (DSM-W-TR). Fourth edition. Ed: Arlington, VA: American Psychiatric Association, 2000.

Spitzer RL, Kroenke K, Williams JBW. Validation and utility of a self-report version of PRIME-MD. Journal of the American Medical Association 1999; 282: 1737–1744.

WHO. SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Version 2.1. Geneva: World Health Organization, 1997.

First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version, Non-patient Edition (SCID-I/NP). New York: Biometrics Research, New York State Psychiatric Institute; 2002.

Kessler RC, Ustun TB. The World Mental Health (WMH) survey initiative version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI). Int J Methods Psychiatr Res 2004; 13: 93–121.

Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes. Diabetes Care 2001; 6: 1069–1078.

Katon W, Von Korff M, Ciechanowski P , et al. Behavioral and clinical factors associated with depression among individuals with diabetes. Diabetes Care 2004; 27: 914–920.

Musselman DL, Evans DL, Nemeroff CB, The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Arch Gen Psychiatr 1998; 55: 580–592.

Mikkelsen RL, Middelboe T, Pisinger C, Stage KB. Anxiety and depression in patients with chronic obstructive pulmonary disease (COPD). A review. Nordic J Psychiatr 2004; 58: 65–70.

Mullen PE, Martin J, Anderson J, et al. The long-term impact of the physical, emotional, and sexual abuse of children: a community study. Child Abuse & Neglect 1996; 20: 7–21.

Roy A. Early parental separation and adult depression. Arch Gen Psychiatr 1985; 42: 987–991.

Felitti VJ, Anda RF, Nordenberg D, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The adverse childhood experiences (ACE) study. Am J Prey Med 1998; 14: 245–258.

Danese A, Pariante CM, Caspi A, et al. Childhood maltreatment predicts adult inflammation in a life-course study. Proc Nat Acad Sci 2007; 104: 1319–1324.

Danese A, Moffitt TE, Pariante CM, et al. Elevated inflammation levels in depressed adults with a history of child-hood maltreatment Arch Gen Psychiatr 2008; 65: 409–415.

Fischer A, Fisher E, Möhlig M, et al. KCNJ11 E23K Affects Diabetes Risk and Is Associated With the Disposition Index: Results of two independent German cohorts. Diabetes Care 2008; 31: 87–89.

Engum A, Mykletun A, Midthjell K, et al. Depression and Diabetes: A large population-based study of sociodemo-graphic, lifestyle, and clinical factors associated with depression in type 1 and type 2 diabetes. Diabetes Care 2005; 28: 1904–1909.

Blazer DG, Moody-Ayers S, Craft-Morgan J, et al. Depression in diabetes and obesity: Racial/ethnic/gender issues in older adults. J Psychosom Res 2002; 53: 913–916.

DeGroot M, Anderson RM, Freedland KE, et al. Association of depression and diabetes complications: a meta-analysis. Psychosom Med 2001; 63: 619–630.

Goldberg D, Privett M, Ustun B, et al. The effects of detection and treatment on the outcome of major depression in primary care: a naturalistic study in 15 cities. Br J Gen Pract 1998; 48: 1840–1844.

Simon GE. Long-term prognosis of depression in primary care. Bull Warld Health Organ 2000; 78: 439–445.

Lustman PJ, Griffith IS, Freedland KE, et al. The course of major depression in diabetes Gen Hasp Psychiatr 1997; 19: 138–143.

Peyrot M, Rubin RR. Persistence of depressive symptoms in diabetic adults. Diabetes Care 1999; 22: 448–452.

Grigsby AB, Anderson RJ, Freedland KE, et al. Prevalence of anxiety in adults with diabetes: a systematic review. J Psychosom Res 2002; 53: 1053–1060.

Mollema ED, Snoek FJ, Adér HJ, et al. Insulin-treated diabetes patients with fear of self-injecting or fear of self-testing: psychological comorbidity and general well-being. J Psychosam Res 2001; 51: 665–672.

Snoek F, Mollema E, Heine R, et al. Development and validation of the dia-betes fear of injecting and self-testing questionnaire (D-FISQ): first findings. Diabetic Mecl1997; 14: 871–876.

Karlson B, Agardh CD. Burden of illness, metabolic control and complications in relation to depressive symp-toms in IDDM patients. Diabetic Med 1997; 14: 1066–1072.

Polonsky WH, Fisher L, Guzman S, et al. Psychological Insulin Resistance in Patients With Type 2 Diabetes: The scope of the problem. Diabetes Care 2005; 28: 2543–2545.

Petrak F, Stridde E, Leverkus F, et al. Development and validation of a new measure to evaluate psychological resistance to insulin treatment Diabetes Care 2007; 30: 2199–2204.

Griva K, Myers LB, Newman S, Illness perceptions and self-efficacy beliefs in adolescents and young adults with insulin dependent diabetes mellitus. Psychology & Health 2000; 15:556–561.

Predicting attendance at diabetes clinic: a self-regulatory approach. British Psychological Society Division of Health Psychology Annual Conference; 2000; University of Kent at Canterbury England.

The self-regulatory model: a frame-work for chronic illness. British Psychological Society Division of Health Psychology Annual Conference; 1999; Leeds, England.

Wade AN, Farmer AJ, Frech DP, Association of beliefs about illness and medication with self-care activities in non-insulin treated type 2 diabetes. Diabetic Med 2004; 21: 52.

Skinner TC, Hampson SE. Social support and personal models of diabetes in relation to self-care and well-being in adolescents with type 1 diabetes melli-tus. JAdolesc 1998; 21: 703–715.

Skinner TC, Hampson SE, Fife-Schaw C, . Personality, personal model beliefs and self-care in adolescents and young adults with Type 1 diabetes. Health Psychol 2002; 21: 61–70.

The illness beliefs of people newly diag-nosed with type 2 diabetes: results from the DESMOND pilot study. 41st EASD Annual Meeting; 2005; Athens, Greece. http://87.234.226.93/easd_intranet/upapplications/upfilewalker/fwdown-load2client.asp?sid785702818 [Accessed 22 August 2008] .

Skinner TC, Howells L, Greene S, et al. Development, reliability and validity of the Diabetes Illness Representations Questionnaire: four studies with ado-lescents. Diabetic Med 2003; 20: 283–289.

Illness representations and well-being in newly diagnosed and long-standing patients with Type 2 diabetes. British Psychological Society Division of Health Psychology Annual Conference; 2002; Sheffield, England.

Law G, Kelly T, Huey D, et al. Self-management and well-being in adoles-cents with diabetes mellitus: do illness representations play a regulatory role.J Adolesc Health 2002; 31: 381–385.

Hampson S, Glasgow R, Strycker L, Beliefs versus feelings: a comparison of personal models and depression for predicting multiple outcomes in dia-betes. Br J Health Psychol 2000; 5: 27–40.

Knol MJ, Twisk JWR, Beekman ATF, et al. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetalogia 2006; 49: 837–45.

Eriksson A-K, Ekbom A, Granath F , et al. Psychological distress and risk of pre-diabetes and Type 2 diabetes in a prospective study of Swedish middle-aged men and women. Diabetic Med 2008; 25: 834–842.

Ciechanowski PS, Katon WJ, Russo JE, Depression and diabetes: impact of depressive symptoms on adherence, function and costs. Arch Int Med 2000; 160: 3278–3285.

Lin EHB, Katon W, Von Korff, M, et al. Relationship of depression and dia-betes self-care, medication adherence, and preventive care. Diabetes Care 2004; 27: 2154–2160.

Lustman PJ, Anderson RJ, Freedland KE, et al. Depression and poor gly-cemic control. A meta-analytic review of the literature. Diabetes Care 2000; 23: 934–942.

Katon WJ, Rutter C, Simon G, et al. The association of comorbid depression with mortality in patients with type 2 diabetes. Diabetes Care 2005; 28: 2668–2672.

Ismail K, Winkley K, Stahl D, et al. A cohort study of people with diabetes and their first foot ulcer: the role of depression on mortality. Diabetes Care 2007; 30: 1473–1479.

Nakahara R, Yoshiuchi K, Kumano H, et al. Prospective study on influence of psychosocial factors on glycemic control in Japanese patients with type 2 dia-betes. Psychosomatics 2006; 47: 240 246.

Egede LE, Nietert PJ, Zheng D, Depression and all-cause and coronary mortality among adults with and with-out diabetes. Diabetes Care 2005; 28: 1339–1345.

Black SA, Markides KS, Ray LA, Depression predicts increased incidence of adverse health outcomes in older Mexican Americans with type 2 diabetes. Diabetes Care 2003; 26: 2822–2828.

Pennix WJH, Beakman ATF, Honig A, Depression and cardiac mortality. Arch General Psy chiatr 2001; 58: 221–227.

McCaffery JM, Frasure-Smith N, Dube M-P, et al. Common genetic vulnerabil-ity to depressive symptoms and coro-nary artery disease: a review and development of candidate genes related to inflammation and serotonin. Psychosom Med 2006; 68: 187–200.

Brotman DJ, Golden SH, Wittstein IS, The cardiovascular toll of stress. The Lancet 2007; 22: 1089–1100.

Musselman DL, Tomer A, Manatunga AK, et al. Exaggerated platelet reactivity in major depression. Am J Psychiatr 1996; 153: 1313–1317.

Frey B, Binder T, Teufelsbauer H. Heart rate variability and patient out-come in advanced heart failure. J Am Coll Cardiol1993; 21: 286A.

Carney RM, Saunders RD, Freedland KE, et al. Association of depression with reduced heart rate variability in coro-nary artery disease. Am J Cardiol 1995; 76: 562–564.

Stunkard AJ, Faith MS, Allison KC. Depression and obesity. Biol Psychiatr 2003; 54: 330–337.

Evans J, MacDonald T, Leese G, et al. Impact of type 1 and type 2 diabetes on patterns and costs of drug prescribing: a population-based study. Diabetes Care 2000; 23: 770–774.

Everson S, Maty S, Lynch J, et al. Epidemiologic evidence for the rela-tion between socioeconomic status and depression, obesity, and diabetes. J Psychosom Res 2002; 53: 891–895.

Riolo SA, Nguyen TA, Greden JF, King CA. Prevalence of depression by race/ethnicity: findings from the National Health and Nutrition Examination Survey III. AmJPub Health 2005; 95: 998–1000.

Lin N, Ye X, Ensel WM, Social support and depressed mood: A structural analysis. J Health Soc Behav 1999; 40: 344–359.

DoH. Quality and Outcomes Frame-work Information, 2006. //www.dh.gov.uk/en/healthcare/prima-rycare/primarycarecontacting/QOF/DH_4125653 [Accessed 22 August 2008].

NICE. Depression: management of depression in primary and secondary care. London: NICE, 2004. http://www.nice.org.uk/Guidance/CG23 [Accessed 22 August 2008].

Lustman P, Freedland K, Griffith L, et al. Fluoxetine for depression in diabetes: a randomized double-blind placebo-controlled trial. Diabetes Care 2000; 23: 618–623.

Lustman PJ, Griffith IS, Clouse RE, et al. Effects of nortriptyline on depres-sion and glucose regulation in diabetes: results of a double-blind placebo-controlled trial. 2nd edn. Psychosom Mecl1997; 59: 241–250.

Lustman PJ, Clouse RE, Nix BD, et al. Sertraline for prevention of depression recurrence in diabetes mellitus. Arch Gen Psychiatr 2006; 63: 521–529.

Paige-Hyvarinen M, Wahlbeck K, Eriksson J . Quality of life and meta-bolic status in mildly depressed women with type 2 diabetes treated with parox-e tine: A single-blind randomised placebo controlled trial. BMC Fam Prad 2003; 4: 7.

Huang X, Song L, Li T, The effect of social support on type II diabetes with depression. Chinese J Clin Psychol 2001; 9: 187–189.

Lustman PJ, Griffith IS, Freedland KE, et al. Cognitive behaviour therapy for depression in type 2 diabetes mellitus. A randomized controlled trial. Ann Intern Med 1998; 129: 613–621.

Katon WJ, Von Korff MV, Lin EHB , et al. The pathways study a randomized trial of collaborative care in patients with diabetes and depression. Arch Gen Psychiatr 2004; 61: 1042–1049.

Williams JVV, Katon W, Lin EHB, et al. The effectiveness of depression care management on diabetes-related out-comes in older patients. Ann Intern Med 2004; 140: 1015–1024.

Bogner HR, Morales KH, Post EP, et al. Diabetes, depression and death: a ran-domized controlled trial of a depres-sion treatment program for older adults based in primary care (PROSPECT). Diabetes Care 2007; 30: 3005–3010.

Downloads

Published

2008-11-01

How to Cite

Winkley, K. (2008). The epidemiology of depression in diabetes. International Diabetes Nursing, 5(3), 91–96. https://doi.org/10.1002/edn.117

Issue

Section

Review Article